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Abstract

Background and Objectives:

Dengue fever a mosquito borne viral infection poses an serious situation due to lack of antiviral drugs or vaccine.

[1]

Worldwide, an estimated 2.5 billion people are at risk of infection.

[2]

It is estimated that more than 50 million infections occur each year, of which 500,000 hospitalizations are of dengue haemorrhagic fever with the case fatality rate exceeding 5% in some areas. The objective of this research was to study the clinical profile in different serological diagnostic parameters of dengue fever.

Methodology:

The present study was conducted in Department of Medicine, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum In patients with dengue fever from January 2014 to December 2014. The study design was one year cross-sectional study. A total of 180 dengue fever patients were studied.

Results:

Out of 180 patients 72.22% of the patients were males and male to female ratio was 2.6: 1

In the study all the patients presented with fever (100%).

In this study 127 (70.56%) patients presented with melaena, the p value was 0.025

In the present study 113 (62.78%) patients presented with rash. p = 0.045.

Platelet count of 20000 to 49999/cumm was in 51 patients (28.33%) with a p = 0.010.

In this study serum creatinine levels were raised in 15% of the patients and the value was p = 0.029

Conclusion and Interpretation:

The findings of this study highlight that clinical profile of dengue fever based on clinical features viz. rash, and laboratory parameters that is, platelet count, serum creatinine which showed significant variations in different dengue serological tests.

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