Review of selected herbal phytoconstituents for potential melanoma treatment

Authors

Bhaskar Kallappa Kurangi, Dr. Prabhakar Kore Basic Science Research Center, KLE Academy of Higher Education and Research, Belagavi, Karnataka, Indi
Sunil Satyappa Jalalpure, Dr. Prabhakar Kore Basic Science Research Center, KLE Academy of Higher Education and Research, Belagavi, Karnataka, Indi

Abstract

Malignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. The current chemotherapies have a relatively low success rate due to the development of multidrug resistance and side effects. Hence, there is need of discovering new compounds that are safe and more effective against melanoma to improve the efficiency and to lower the treatment cost for cancer care. Melanoma chemoprevention with natural herbal phytoconstituents is an emerging strategy to prevent, cure, or treat melanoma. This review summarizes the latest research in melanoma chemoprevention and treatment using the herbal phytoconstituents. Relevant mechanisms involved in the pharmacological effects of these phytochemical are discussed. Phytoconstituents that are discussed in this review are carotenoids, flavonoids, some polyphenols, piperine alkaloid, and sulforaphane having high anticancer potential mostly to be used for the treatment of melanoma.

Recommended Citation

Kurangi, Bhaskar Kallappa and Jalalpure, Sunil Satyappa (2018) "Review of selected herbal phytoconstituents for potential melanoma treatment," Indian Journal of Health Sciences and Biomedical Research KLEU: Vol. 11: Iss. 1, Article 2.
DOI: https://doi.org/10.4103/kleuhsj.kleuhsj_319_17
Available at: https://kleijhsbr.researchcommons.org/journal/vol11/iss1/2

Pages

3

Last Page

11

Copyright

© 2018 Indian Journal of Health Sciences and Biomedical Research KLEU | Published by Wolters Kluwer – Medknow