Preparation and development of polyherbal formulation of medicinal plants for antiarthritic activity
Abstract
AIM AND OBJECTIVES:
The main objective of the present research was to prepare and develop polyherbal formulation of medicinal plants such as seed coat and kernel of
Terminalia chebula
and
Terminalia bellirica
and dried fruits of
Emblica officinalis
and evaluate the antiarthritic activity using animal models.
MATERIALS AND METHODS:
Using seed coat and kernel of
T. chebula
and
T. bellirica
and dried fruits of
E. officinalis
, Polyherbal formulation was prepared. Further antiarthritic activity of the prepared formulation was tested in female Wistar rats, using Freund's complete adjuvant as an inducing agent.
RESULTS:
The antiarthritic activity of polyherbal formulation against Freund's complete adjuvant-induced paw edema shows that all the three doses 250, 500, and 750 mg/kg p.o have significant effects and markedly reduced the swelling of paw.
CONCLUSION:
Polyherbal formulation exerts a significant protective effect against Freund's complete adjuvant-induced paw edema in rats.
Recommended Citation
Chimagave, Supriya S.; Jalalpure, Sunil S.; and Kurangi, Bhaskar K.
(2020)
"Preparation and development of polyherbal formulation of medicinal plants for antiarthritic activity,"
Indian Journal of Health Sciences and Biomedical Research KLEU: Vol. 13:
Iss.
2, Article 9.
DOI: https://doi.org/10.4103/kleuhsj.kleuhsj_163_19
Available at:
https://kleijhsbr.researchcommons.org/journal/vol13/iss2/9
Pages
120
Last Page
126
Copyright
© 2020 Indian Journal of Health Sciences and Biomedical Research KLEU | Published by Wolters Kluwer – Medknow