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Keywords

SCC kidney, Radiation induced GI perforation, Radiotherapy

Abstract

Squamous cell carcinoma (SCC) of the renal pelvis is an uncommon tumor typically linked to chronic renal stone disease. This tumor is inherently aggressive and generally associated with a poor prognosis. We present a case involving a patient with retroperitoneal descending colon perforation in advanced squamous cell carcinoma of kidney probably secondary to radiation. Radiation-induced gastrointestinal perforation necessitates emergency surgery, and there is a lack of high-quality evidence to support the effectiveness of any preventive measures. In this review, we provide an overview of the clinical manifestations, risk factors, mechanisms, and treatments associated with radiation-induced gastrointestinal perforation. A thorough treatment plan is essential for enhancing the quality of life for cancer survivors.

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