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Keywords

Ashmarihar kwatha, Mootrashmari, Osteopontin, Pashanbhedadi kwatha, Urolithiasis

Abstract

Background: Urolithiasis, the formation of urinary stones, is a prevalent global health issue. It commonly causes severe acute back pain and can lead to serious complications such as pyelonephritis or acute renal failure. Kidney stone formation is a common urological problem with a lifetime prevalence of approximately 10% in men and 6% in women. The study aimed to evaluate and compare the clinical effect of Ashmarihar kwatha (AK) and Pashanbhedadi kwatha (PK) in the management of Mootrashmari (∼Urolithiasis).
Material and Method: The primary objective of the study was to assess the clinical efficacy of Ashmarihar kwatha and Pashanbhedadi kwatha in the management of Mootrashmari (urolithiasis) based on symptomatic and stone-related parameters, while the secondary objective was to evaluate the safety and additional therapeutic effects of the interventions through laboratory investigations and ultrasonographic findings. This was an open-labelled randomized comparative clinical trial. A total of 135 cases were screened, and 82 patients diagnosed with Mootrashmari satisfying the study criteria were enrolled. 53 cases were excluded. Participants were randomly assigned to group AK (n=32 completed) and group PK (n=39 completed). Both Kwathas (coarse powder, 10 gm) were administered orally as an internal medication twice a day before food for 60 days.
Result: Both groups showed similar statistical effects across all parameters. However, a statistically highly significant result was obtained in the expulsion of the number of stones in the AK group while PK group showed non-significant improvement within groups.
Conclusion: Ashmarihar kwatha and Pashanbhedadi kwatha both the show statistically similar efficacy between the group in the management of Mootrashmari (∼Urolithiasis).

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92

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